Clostridium difficile Toxin CDT Induces Formation of Microtubule-Based Protrusions and Increases Adherence of Bacteria

Carsten Schwan, Bärbel Stecher, Tina Tzivelekidis, +5

PLoS Pathogens

Microbial ToxinMedical MicrobiologyEfficient Microtubule CaptureToxinologyMedicine +12

Lipolysis-stimulated lipoprotein receptor (LSR) is the host receptor for the binary toxin <i>Clostridium difficile</i> transferase (CDT)

Panagiotis Papatheodorou, Jan E. Carette, George W. Bell, +4

Proceedings of the National Academy of Sciences

Proteinlipid InteractionHost ReceptorToxinologyMicrobial PathogensMolecular Biology +18

The binary toxin CDT enhances Clostridium difficile virulence by suppressing protective colonic eosinophilia

Carrie A. Cowardin, Erica L. Buonomo, Mahmoud Saleh, +10

Nature Microbiology

Microbial ToxinToxinologyMucosal ImmunologyProtective Colonic EosinophiliaClostridium Difficile Virulence +9

<i>Clostridium difficile</i> toxin CDT hijacks microtubule organization and reroutes vesicle traffic to increase pathogen adherence

Carsten Schwan, Anna S. Kruppke, Thilo Nölke, +5

Proceedings of the National Academy of Sciences

Microtubule OrganizationToxinologyMicrobial PathogensMicrotubule RestructuringCytoskeleton +22

Membrane Translocation of Binary Actin-ADP-Ribosylating Toxins from Clostridium difficile and Clostridium perfringens Is Facilitated by Cyclophilin A and Hsp90

Eva Kaiser, Claudia Kroll, Katharina Ernst, +6

Infection and Immunity

ImmunologyBacteriologyCyclophilin ACytoskeletonToxins A +16

GPCR-induced calcium transients trigger nuclear actin assembly for chromatin dynamics

Ying Wang, Alice Sherrard, Bing Zhao, +7

Nature Communications

Reelin Signals through Apolipoprotein E Receptor 2 and Cdc42 to Increase Growth Cone Motility and Filopodia Formation

Jost Leemhuis, Elisabeth Bouché, Michael Frotscher, +8

Journal of Neuroscience

CytoskeletonCell GrowthMature BrainCellular NeurobiologyCellular Physiology +19

Domain organization of Legionella effector SetA

Thomas Jank, Kira E. Böhmer, Tina Tzivelekidis, +3

Cellular Microbiology

Protein SecretionMicrobial PathogensLegionella PneumophilaGlycobiologyMolecular Biology +17

Selection of Nanobodies that Block the Enzymatic and Cytotoxic Activities of the Binary Clostridium Difficile Toxin CDT

Mandy Unger, Anna Marei Eichhoff, Lucas Schumacher, +14

Scientific Reports

Molecular Characteristics of Clostridium perfringens TpeL Toxin and Consequences of Mono-O-GlcNAcylation of Ras in Living Cells

Gregor Guttenberg, Sven Hornei, Thomas Jank, +5

Journal of Biological Chemistry