Hypoxia-mediated induction of endothelial cell interleukin-1 alpha. An autocrine mechanism promoting expression of leukocyte adhesion molecules on the vessel surface.

Revati Shreeniwas, S Koga, Mehmet Çağrı Karakurum, +7

Journal of Clinical Investigation

Vessel SurfaceCell AdhesionImmunologyImmune RegulationInflammation +16

Membrane Translocation of Binary Actin-ADP-Ribosylating Toxins from Clostridium difficile and Clostridium perfringens Is Facilitated by Cyclophilin A and Hsp90

Eva Kaiser, Claudia Kroll, Katharina Ernst, +6

Infection and Immunity

ImmunologyBacteriologyCyclophilin ACytoskeletonToxins A +16

Cyclophilin A facilitates translocation of the<i>Clostridium botulinum</i>C2 toxin across membranes of acidified endosomes into the cytosol of mammalian cells

Eva Kaiser, Sascha Pust, Claudia Kroll, +1

Cellular Microbiology

Protein SecretionToxinologyMolecular BiologyCyclophilin AAcidified Endosomes +20

Role of CypA and Hsp90 in membrane translocation mediated by anthrax protective antigen

Lydia Dmochewitz, Maren Lillich, Eva Kaiser, +7

Cellular Microbiology

Protein SecretionImmunologyAntigen ProcessingCellular PhysiologyDiphtheria Toxin +17

Selective and specific internalization of clostridial C3 ADP-ribosyltransferases into macrophages and monocytes

Jörg Fahrer, Jasmin Kuban, Karin Heine, +5

Cellular Microbiology

ImmunologyProtein SynthesisInflammationMedical MicrobiologySelective Uptake Mechanism +16

FK506‐binding protein 51 interacts with<i>Clostridium botulinum</i>C2 toxin and FK506 inhibits membrane translocation of the toxin in mammalian cells

Eva Kaiser, Natalie Böhm, Katharina Ernst, +6

Cellular Microbiology

Protein SecretionToxinologyMolecular BiologyProtein 51Fk506 Inhibits +20

Cyclophilin-Facilitated Membrane Translocation as Pharmacological Target to Prevent Intoxication of Mammalian Cells by Binary Clostridial Actin ADP-Ribosylated Toxins

Katharina Ernst, Simon Langer, Eva Kaiser, +9

Journal of Molecular Biology

Microbial ToxinCyclophilin-facilitated Membrane TranslocationBiochemistryMammalian CellsMedicine +7

The Long-Lived Nature of <i>Clostridium perfringens</i> Iota Toxin in Mammalian Cells Induces Delayed Apoptosis

Hanna Hilger, Sascha Pust, Guido von Figura, +4

Infection and Immunity

ToxinologyApoptosisCell DeathCell Death MechanismsToxicological Mechanism +15

Formation of a Biologically Active Toxin Complex of the Binary <i>Clostridium botulinum</i> C2 Toxin without Cell Membrane Interaction

Eva Kaiser, Gerd Haug, Marion Hliscs, +2

Biochemistry

A Cell-permeable Fusion Toxin as a Tool to Study the Consequences of Actin-ADP-ribosylation Caused by the Salmonella enterica Virulence Factor SpvB in Intact Cells

Sascha Pust, Henrike Hochmann, Eva Kaiser, +4

Journal of Biological Chemistry

Microbial ToxinIntact CellsMicrobial PathogensNatural SciencesVirulence Factor +12