Qiaoshuai Lan

Inhibition of SARS-CoV-2 (previously 2019-nCoV) infection by a highly potent pan-coronavirus fusion inhibitor targeting its spike protein that harbors a high capacity to mediate membrane fusion

Shuai Xia, Meiqin Liu, Chao Wang et al. · Cell Research · 2020 · 1.4K citations · Full text

Life Sciences, Infectious Diseases, Molecular Biology +16

Fusion mechanism of 2019-nCoV and fusion inhibitors targeting HR1 domain in spike protein

Shuai Xia, Yun Zhu, Meiqin Liu et al. · Cellular and Molecular Immunology · 2020 · 758 citations · Full text

Life Sciences, Biomedical Sciences, Molecular Biology +10

V367F Mutation in SARS-CoV-2 Spike RBD Emerging during the Early Transmission Phase Enhances Viral Infectivity through Increased Human ACE2 Receptor Binding Affinity

Junxian Ou, Zhonghua Zhou, Ruixue Dai et al. · Journal of Virology · 2021 · 113 citations · Full text

Life Sciences, Infectious Diseases, Molecular Biology +17

Structural and functional basis for pan-CoV fusion inhibitors against SARS-CoV-2 and its variants with preclinical evaluation

Shuai Xia, Qiaoshuai Lan, Yun Zhu et al. · Signal Transduction and Targeted Therapy · 2021 · 68 citations · Full text

Life Sciences, Infectious Diseases, Pharmacology +10

Potent MERS-CoV Fusion Inhibitory Peptides Identified from HR2 Domain in Spike Protein of Bat Coronavirus HKU4

Shuai Xia, Qiaoshuai Lan, Jing Pu et al. · Viruses · 2019 · 40 citations · Full text

Life Sciences, Infectious Diseases, Molecular Biology +16