Tracking SARS-CoV-2 Omicron diverse spike gene mutations identifies multiple inter-variant recombination events

Junxian Ou, Wendong Lan, Xiaowei Wu, +11

Signal Transduction and Targeted Therapy

V367F Mutation in SARS-CoV-2 Spike RBD Emerging during the Early Transmission Phase Enhances Viral Infectivity through Increased Human ACE2 Receptor Binding Affinity

Junxian Ou, Zhonghua Zhou, Ruixue Dai, +13

Journal of Virology

V367F mutation in SARS-CoV-2 spike RBD emerging during the early transmission phase enhances viral infectivity through increased human ACE2 receptor binding affinity

Junxian Ou, Zhonghua Zhou, Ruixue Dai, +10

Virus StructureVirus AssaysViral EvolutionRbd Beta-sheet ScaffoldEmerging Infectious Diseases +13

Emergence of RBD mutations in circulating SARS-CoV-2 strains enhancing the structural stability and human ACE2 receptor affinity of the spike protein

Junxian Ou, Zhonghua Zhou, Ruixue Dai, +8

Rbd MutantsStructural StabilityImmunologyViral PathogenesisMolecular Biology +14

Molecular Typing and Rapid Identification of Human Adenoviruses Associated With Respiratory Diseases Using Universal PCR and Sequencing Primers for the Three Major Capsid Genes: Penton Base, Hexon, and Fiber

Xiaowei Wu, Jing Zhang, Wendong Lan, +7

Frontiers in Microbiology

Human Adenoviruses AssociatedViral DiagnosticsImmunologyMolecular BiologyMolecular Typing +15

Temperature dependence of the SARS-CoV-2 affinity to human ACE2 determines COVID-19 progression and clinical outcome

Zhonghua Zhou, Ziyi Yang, Junxian Ou, +4

Computational and Structural Biotechnology Journal

Virus StructureViral PersistenceEarly StageViral Spike ProteinCovid-19 Pandemic +13

A Survey of Recent Adenoviral Respiratory Pathogens in Hong Kong Reveals Emergent and Recombinant Human Adenovirus Type 4 (HAdV-E4) Circulating in Civilian Populations

Jing Zhang, June Kang, Shoaleh Dehghan, +6

Viruses

Comparative Genomic Analysis of Re-emergent Human Adenovirus Type 55 Pathogens Associated With Adult Severe Community-Acquired Pneumonia Reveals Conserved Genomes and Capsid Proteins

Zetao Cheng, Yuqian Yan, Shuping Jing, +11

Frontiers in Microbiology

Tracking SARS-CoV-2 Omicron diverse spike gene mutations identifies multiple inter-variant recombination events

Junxian Ou, Wendong Lan, Xiaowei Wu, +10

Viral EvolutionDelta Spike ProteinEmerging Infectious DiseasesDelta VariantsGenetics +12

Generation of Human Embryonic Stem Cell-Derived Lung Organoids for Modeling Infection and Replication Differences between Human Adenovirus Types 3 and 55 and Evaluating Potential Antiviral Drugs

Shanshan Zhao, Xiaowei Wu, Zhihong Tan, +10

Journal of Virology