Kelli Glenn

Discovery of RG7388, a Potent and Selective p53–MDM2 Inhibitor in Clinical Development

Qingjie Ding, Zhuming Zhang, Jinjun Liu et al. · Journal of Medicinal Chemistry · 2013 · 583 citations · Full text

Drug Target, Chemical Biology, Cancer Biology +19

Discovery of RG7112: A Small-Molecule MDM2 Inhibitor in Clinical Development

Binh Thanh Vu, Peter M. Wovkulich, Giacomo Pizzolato et al. · ACS Medicinal Chemistry Letters · 2013 · 373 citations · Full text

Drug Target, Cell Death, Small-molecule Mdm2 Inhibitor +17

Preclinical Profile of a Potent γ-Secretase Inhibitor Targeting Notch Signaling with <i>In vivo</i> Efficacy and Pharmacodynamic Properties

Leopoldo Luistro, Wei He, Melissa Smith et al. · Cancer Research · 2009 · 188 citations · Full text

Ro4929097 Ic50, Cancer Biology, Tumor Biology +17

Positive allosteric modulation of GABAA receptors by a novel antiepileptic drug cenobamate

Ramesh Sharma, Michiko Nakamura, Chiranjivi Neupane et al. · European Journal of Pharmacology · 2020 · 120 citations

Molecular Pharmacology, Positive Allosteric Modulation, Neuromodulation (Medicine) +6

Discovery of Potent and Orally Active p53-MDM2 Inhibitors RO5353 and RO2468 for Potential Clinical Development

Zhuming Zhang, Xin‐Jie Chu, Jinjun Liu et al. · ACS Medicinal Chemistry Letters · 2013 · 86 citations · Full text

Medicinal Chemistry, Pharmaceutical Chemistry, Chemoprevention Strategy +14