Thom M. Molenaar

Conserved crosstalk between histone deacetylation and H3K79 methylation generates DOT1L‐dose dependency in HDAC1‐deficient thymic lymphoma

Hanneke Vlaming, Chelsea McLean, Tessy Korthout et al. · The EMBO Journal · 2019 · 44 citations · Full text

Medicine, Cancer Biology, Molecular Biology +16

Dot1 promotes H2B ubiquitination by a methyltransferase-independent mechanism

Tibor van Welsem, Tessy Korthout, Reggy Ekkebus et al. · Nucleic Acids Research · 2018 · 36 citations · Full text

Life Sciences, Genetics, Molecular Biology +13

Direct screening for chromatin status on DNA barcodes in yeast delineates the regulome of H3K79 methylation by Dot1

Hanneke Vlaming, Thom M. Molenaar, Tibor van Welsem et al. · eLife · 2016 · 34 citations · Full text

Life Sciences, Genetics, Molecular Biology +14

CRISPR screens in sister chromatid cohesion defective cells reveal PAXIP1-PAGR1 as regulator of chromatin association of cohesin

Janne J. M. van Schie, Klaas de Lint, Thom M. Molenaar et al. · Nucleic Acids Research · 2023 · 13 citations · Full text

Life Sciences, Molecular Biology, Molecular Genetics +17