Chelsea McLean

Patient-derived organoids can predict response to chemotherapy in metastatic colorectal cancer patients

Salo Ooft, Fleur Weeber, Krijn K. Dijkstra et al. · Science Translational Medicine · 2019 · 826 citations

Medicine, Oncology, Pharmacology +17

Prospective experimental treatment of colorectal cancer patients based on organoid drug responses

Salo Ooft, Fleur Weeber, Luuk J. Schipper et al. · ESMO Open · 2021 · 145 citations · Full text

Medicine, Oncology, Pharmacology +16

Antagonism between DNA and H3K27 Methylation at the Imprinted Rasgrf1 Locus

Anders M. Lindroth, Yoon Jung Park, Chelsea McLean et al. · PLoS Genetics · 2008 · 124 citations · Full text

Medicine, Genetics, Molecular Biology +17

Whole-genome sequencing of bladder cancers reveals somatic CDKN1A mutations and clinicopathological associations with mutation burden

Jean‐Baptiste Cazier, Srinivasa R. Rao, Chelsea McLean et al. · Nature Communications · 2014 · 115 citations · Full text

Medicine, Molecular Biology, Oncology +17

Multiple low dose therapy as an effective strategy to treat EGFR inhibitor-resistant NSCLC tumours

João M. Fernandes Neto, Ernest Nadal, Evert Bosdriesz et al. · Nature Communications · 2020 · 92 citations · Full text

Medicine, Oncology, Pharmacology +15