Juan I. Aróstegui

Pyogenic Bacterial Infections in Humans with MyD88 Deficiency

Horst von Bernuth, Capucine Pïcard, Zhongbo Jin et al. · Science · 2008 · 1.3K citations · Full text

Inflammation, Toll-like Receptors, Nine Children +14

The NLRP3 inflammasome is released as a particulate danger signal that amplifies the inflammatory response

Alberto Baroja‐Mazo, Fatima Martín‐Sánchez, Ana Isabel Gómez Córdoba et al. · Nature Immunology · 2014 · 777 citations

Inflammation, Anti-inflammatory, Inflammatory Disease +11

B cell–helper neutrophils stimulate the diversification and production of immunoglobulin in the marginal zone of the spleen

Irene Puga, Montserrat Cols, Carolina Barra et al. · Nature Immunology · 2011 · 711 citations

Lymphocyte Development, Immune Cell Development, Granulocyte +13

Clinical Features and Outcome of Patients With IRAK-4 and MyD88 Deficiency

Capucine Pïcard, Horst von Bernuth, Pegah Ghandil et al. · Medicine · 2010 · 420 citations · Full text

MCC950 closes the active conformation of NLRP3 to an inactive state

Ana Tapia‐Abellán, Diego Angosto-Bazarra, Helios Martínez‐Banaclocha et al. · Nature Chemical Biology · 2019 · 414 citations · Full text

Active Conformation, Inactive State, Biophysics +1