Helios Martínez‐Banaclocha

MCC950 closes the active conformation of NLRP3 to an inactive state

Ana Tapia‐Abellán, Diego Angosto-Bazarra, Helios Martínez‐Banaclocha et al. · Nature Chemical Biology · 2019 · 436 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +9

P2X7 receptor induces mitochondrial failure in monocytes and compromises NLRP3 inflammasome activation during sepsis

Juan José Martínez-García, Helios Martínez‐Banaclocha, Diego Angosto-Bazarra et al. · Nature Communications · 2019 · 250 citations · Full text

Veterinary Medicine, Cell Biology, Immunology +17

Development of an Acrylate Derivative Targeting the NLRP3 Inflammasome for the Treatment of Inflammatory Bowel Disease

Mattia Cocco, Carolina Pellegrini, Helios Martínez‐Banaclocha et al. · Journal of Medicinal Chemistry · 2017 · 162 citations · Full text

Veterinary Medicine, Medicinal Chemistry, Pharmacology +17

A novel Pyrin-Associated Autoinflammation with Neutrophilic Dermatosis mutation further defines 14-3-3 binding of pyrin and distinction to Familial Mediterranean Fever

Fiona Moghaddas, Rafael Llamas, Dominic De Nardo et al. · Annals of the Rheumatic Diseases · 2017 · 148 citations · Full text

Life Sciences, Immunology, Pathobiology +17

NLRP3 inflammasome as prognostic factor and therapeutic target in primary progressive multiple sclerosis patients

Sunny Malhotra, Carme Costa, Herena Eixarch et al. · Brain · 2020 · 136 citations · Full text

Life Sciences, Immunology, Molecular Biology +17