Diego Angosto-Bazarra

MCC950 closes the active conformation of NLRP3 to an inactive state

Ana Tapia‐Abellán, Diego Angosto-Bazarra, Helios Martínez‐Banaclocha et al. · Nature Chemical Biology · 2019 · 436 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +9

Cell Volume Regulation Modulates NLRP3 Inflammasome Activation

Vincent Compan, Alberto Baroja‐Mazo, Gloria López‐Castejón et al. · Immunity · 2012 · 399 citations · Full text

Life Sciences, Cell Biology, Immunology +10

P2X7 receptor induces mitochondrial failure in monocytes and compromises NLRP3 inflammasome activation during sepsis

Juan José Martínez-García, Helios Martínez‐Banaclocha, Diego Angosto-Bazarra et al. · Nature Communications · 2019 · 250 citations · Full text

Veterinary Medicine, Cell Biology, Immunology +17

Development of an Acrylate Derivative Targeting the NLRP3 Inflammasome for the Treatment of Inflammatory Bowel Disease

Mattia Cocco, Carolina Pellegrini, Helios Martínez‐Banaclocha et al. · Journal of Medicinal Chemistry · 2017 · 162 citations · Full text

Veterinary Medicine, Medicinal Chemistry, Pharmacology +17

Sensing low intracellular potassium by NLRP3 results in a stable open structure that promotes inflammasome activation

Ana Tapia‐Abellán, Diego Angosto-Bazarra, Cristina Alarcón‐Vila et al. · Science Advances · 2021 · 153 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +17