Diego Angosto-Bazarra

MCC950 closes the active conformation of NLRP3 to an inactive state

Ana Tapia‐Abellán, Diego Angosto-Bazarra, Helios Martínez‐Banaclocha et al. · Nature Chemical Biology · 2019 · 414 citations · Full text

Active Conformation, Inactive State, Biophysics +1

Cell Volume Regulation Modulates NLRP3 Inflammasome Activation

Vincent Compan, Alberto Baroja‐Mazo, Gloria López‐Castejón et al. · Immunity · 2012 · 394 citations · Full text

Inflammation, Signal Transduction, Cell Interaction +9

P2X7 receptor induces mitochondrial failure in monocytes and compromises NLRP3 inflammasome activation during sepsis

Juan José Martínez-García, Helios Martínez‐Banaclocha, Diego Angosto-Bazarra et al. · Nature Communications · 2019 · 238 citations · Full text

Development of an Acrylate Derivative Targeting the NLRP3 Inflammasome for the Treatment of Inflammatory Bowel Disease

Mattia Cocco, Carolina Pellegrini, Helios Martínez‐Banaclocha et al. · Journal of Medicinal Chemistry · 2017 · 156 citations · Full text

Gastrointestinal Pharmacology, Immunology, Cell Death +20

Sensing low intracellular potassium by NLRP3 results in a stable open structure that promotes inflammasome activation

Ana Tapia‐Abellán, Diego Angosto-Bazarra, Cristina Alarcón‐Vila et al. · Science Advances · 2021 · 140 citations · Full text