Heparanase 2 Interacts with Heparan Sulfate with High Affinity and Inhibits Heparanase Activity

Flonia Levy‐Adam, Sari Feld, Victoria Cohen‐Kaplan, +6

Journal of Biological Chemistry

Inhibits Heparanase ActivityHeparanase ActivityBiochemistryFull-length Hpa2c ProteinMedicine +13

Macrophage Activation by Heparanase Is Mediated by TLR-2 and TLR-4 and Associates With Plaque Progression

Miry Blich, Amnon Golan, Gil Arvatz, +13

Arteriosclerosis Thrombosis and Vascular Biology

Characterization of a chemically modified plant cell culture expressed human α-Galactosidase-A enzyme for treatment of Fabry disease

Tali Kizhner, Yaniv Azulay, Mariana Hainrichson, +6

Molecular Genetics and Metabolism

GlycobiologyFabry DiseaseMannose StructuresHuman α-Galactosidase-a EnzymeProtein Degradation +14

Heparanase-neutralizing antibodies attenuate lymphoma tumor growth and metastasis

Marina Weissmann, Gil Arvatz, Netanel A. Horowitz, +8

Proceedings of the National Academy of Sciences

Exosome secretion affects social motility in Trypanosoma brucei

Dror Eliaz, Sriram Kannan, Hadassa Shaked, +8

PLoS Pathogens

Protein SecretionSpliced LeaderMolecular BiologyExtracellular MicrovesiclesExosome Biology +14

Heparanase 2 Attenuates Head and Neck Tumor Vascularity and Growth

Miriam Gross-Cohen, Sari Feld, Ilana Doweck, +7

Cancer Research

Tumor BiologyMalignant DiseaseMedicineHpa2 InductionHistopathology +12

A novel human heparanase splice variant, T5, endowed with protumorigenic characteristics

Uri Barash, Victoria Cohen‐Kaplan, Gil Arvatz, +7

The FASEB Journal

BiologyTumor BiologyMedicineGeneticsNatural Sciences +13

Post-transcriptional regulation of heparanase gene expression by a 3′ AU-rich element

Gil Arvatz, Uri Barash, Ofer Nativ, +2

The FASEB Journal

Heparanase Up-regulationMolecular BiologyHeparanase ExpressionTumor BiologyTranscriptional Regulation +16

RNAi interference of XPO1 and Sm genes and their effect on the spliced leader RNA in Trypanosoma brucei

Moshe Biton, Michal Mandelboim, Gil Arvatz, +1

Molecular and Biochemical Parasitology

BiologyAfrican TrypanosomiasisNatural SciencesGeneticsRna Biology +10

Heparanase and cancer progression: New directions, new promises

Gil Arvatz, Marina Weissmann, Neta Ilan, +1

Human Vaccines & Immunotherapeutics

Tumor MicroenvironmentMalignant DiseaseMedicineTumor GrowthHistopathology +13