Charge variants characterization of a monoclonal antibody by ion exchange chromatography coupled on-line to native mass spectrometry: Case study after a long-term storage at +5 °C

Y. Leblanc, C. Ramon, Nicolas Bihoreau, +1

Journal of Chromatography B

Charge Variants CharacterizationAged Monoclonal AntibodyImmunologyBiological Mass SpectrometryBioanalysis +17

Chronic lymphocytic leukaemia cells are efficiently killed by an anti‐CD20 monoclonal antibody selected for improved engagement of FcγRIIIA/CD16

Christophe de Romeuf, Charles‐Antoine Dutertre, Magali Le Garff‐Tavernier, +13

British Journal of Haematology

Fast analysis of recombinant monoclonal antibodies using IdeS proteolytic digestion and electrospray mass spectrometry

Guillaume Chevreux, Nolwenn Tilly, Nicolas Bihoreau

Analytical Biochemistry

Fast AnalysisMedicineNatural SciencesBioanalysisMass Spectrometry +11

Selection of a human anti-RhD monoclonal antibody for therapeutic use: Impact of IgG glycosylation on activating and inhibitory FcγR functions

Sophie Sibéril, Christophe de Romeuf, Nicolas Bihoreau, +13

Clinical Immunology

AllergyTherapeutic UseImmunologyAntibody ScreeningHumoral Immunity +9

Site-specific N-glycan characterization of human complement factor H

François Fenaille, Maxime Le Mignon, Catherine Groseil, +4

Glycobiology

HistocompatibilityImmunologyGlycobiologyCfh GlycosylationProtein Purification +14

Copper‐atom identification in the active and inactive forms of plasma‐derived FVIII and recombinant FVIII‐ΔII

Nicolas Bihoreau, Serge Pin, Anne‐Marie de Kersabiec, +2

European Journal of Biochemistry

EngineeringCopper IonMolecular BiologyChemistryChemical Biology +17

Middle-up analysis of monoclonal antibodies after combined IgdE and IdeS hinge proteolysis: Investigation of free sulfhydryls

Valegh Faid, Y. Leblanc, Nicolas Bihoreau, +1

Journal of Pharmaceutical and Biomedical Analysis

Immunocytochemical TechniqueImmunologyGlycobiologyMabs StructureProtein Purification +15

DNA aptamer affinity ligands for highly selective purification of human plasma-related proteins from multiple sources

Cynthia Forier, Egisto Boschetti, Mohamed Ouhammouch, +9

Journal of Chromatography A

Characterization of Human Serum Albumin isoforms by ion exchange chromatography coupled on-line to native mass spectrometry

Y. Leblanc, Nicolas Bihoreau, Guillaume Chevreux

Journal of Chromatography B

BiochemistryGas ChromatographyMedicineNatural SciencesBioanalysis +10

A generic method for intact and subunit level characterization of mAb charge variants by native mass spectrometry

Y. Leblanc, Valegh Faid, Matthew Lauber, +3

Journal of Chromatography B

BiochemistryNatural SciencesMedicineBioanalysisMass Spectrometry +9