Raymond J. Deshaies

Protacs: Chimeric molecules that target proteins to the Skp1–Cullin–F box complex for ubiquitination and degradation

Kathleen M. Sakamoto, Kyung B. Kim, Akiko Kumagai et al. · Proceedings of the National Academy of Sciences · 2001 · 2.3K citations · Full text

A subfamily of stress proteins facilitates translocation of secretory and mitochondrial precursor polypeptides

Raymond J. Deshaies, B. Koch, Margaret Werner‐Washburne et al. · Nature · 1988 · 1.5K citations

Stress Proteins, Protein Secretion, Signal Transduction +11

Role of Rpn11 Metalloprotease in Deubiquitination and Degradation by the 26 <i>S</i> Proteasome

Rati Verma, L. Aravind, Robert Oania et al. · Science · 2002 · 1K citations · Full text

A Complex of Cdc4p, Skp1p, and Cdc53p/Cullin Catalyzes Ubiquitination of the Phosphorylated CDK Inhibitor Sic1p

R. M. Renny Feldman, Craig C. Correll, Kenneth B. Kaplan et al. · Cell · 1997 · 809 citations · Full text

Protein Function, Signal Transduction, Signaling Pathway +8

Alcohol-abuse drug disulfiram targets cancer via p97 segregase adaptor NPL4

Zdeněk Škrott, Martin Mistrík, Klaus Kaae Andersen et al. · Nature · 2017 · 759 citations

Drug Target, Drug Targeting, Medicine +6