PPARdelta activation induces metabolic and contractile maturation of human pluripotent stem cell-derived cardiomyocytes

Nadeera M. Wickramasinghe, David Sachs, Bhavana Shewale, +23

Cell stem cell

CardiomyopathyInduced Pluripotent Stem CellMolecular PhysiologyMedicineInduced Pluripotent Stem Cells +10

Gene expression profiling for human iPS-derived motor neurons from sporadic ALS patients reveals a strong association between mitochondrial functions and neurodegeneration

Chrystian Junqueira Alves, Rafael Dariolli, Frederico M. H. Jorge, +7

Frontiers in Cellular Neuroscience

Neurodegenerative DiseasesSystems BiologyAmyotrophic Lateral SclerosisSporadic AlsMitochondrial Function +13

Variation of mechanical properties and quantitative proteomics of VSMC along the arterial tree

Carla Luana Dinardo, Gabriela Venturini, Enhua H. Zhou, +9

American Journal of Physiology-Heart and Circulatory Physiology

Porcine Adipose Tissue-Derived Mesenchymal Stem Cells Retain Their Proliferative Characteristics, Senescence, Karyotype and Plasticity after Long-Term Cryopreservation

Rafael Dariolli, Vinícius Bassaneze, Juliana Sanajotti Nakamuta, +3

PLoS ONE

Plexin-B2 orchestrates collective stem cell dynamics via actomyosin contractility, cytoskeletal tension and adhesion

Chrystian Junqueira Alves, Rafael Dariolli, Jonathan C. Haydak, +16

Nature Communications

Heart failure alters matrix metalloproteinase gene expression and activity in rat skeletal muscle

Robson Francisco Carvalho, Rafael Dariolli, Luís Antônio Justulin, +5

International Journal of Experimental Pathology

Cardiac MuscleHeart FailureHeart Failure AltersMmp Mrna ExpressionCardiovascular Function +19

Cardioprotection Conferred by Sitagliptin Is Associated with Reduced Cardiac Angiotensin II/Angiotensin-(1-7) Balance in Experimental Chronic Kidney Disease

Juliana Isa Beraldo, Acaris Benetti, Flávio A. Borges-Júnior, +8

International Journal of Molecular Sciences

HypertensionHeart FailureCardiovascular PharmacologySitagliptin Is AssociatedMetabolic Syndrome +18

Mechanisms underlying the inhibitory effects of uroguanylin on NHE3 transport activity in renal proximal tubule

Lucília M. A. Lessa, Luciene R. Carraro‐Lacroix, Renato O. Crajoinas, +5

American Journal of Physiology-Renal Physiology

Renal InflammationWater HomeostasisCellular PhysiologyMolecular PharmacologyRenal Function +19

Long-term single-cell passaging of human iPSC fully supports pluripotency and high-efficient trilineage differentiation capacity

Estela Cruvinel, Isabella Ogusuku, Rosanna Cerioni, +12

SAGE Open Medicine

Investigational Treatments for COVID‐19 may Increase Ventricular Arrhythmia Risk Through Drug Interactions

Meera Varshneya, Itziar Irurzun‐Arana, Chiara Campana, +4

CPT Pharmacometrics & Systems Pharmacology