Yan Ge

The A946T variant of the RNA sensor IFIH1 mediates an interferon program that limits viral infection but increases the risk for autoimmunity

Jacquelyn A. Gorman, Christian Hundhausen, John S. Errett et al. · Nature Immunology · 2017 · 136 citations · Full text

Interferon Program, Autoimmune Disease, A946t Variant +9

Globular adiponectin inhibits GnRH secretion from GT1-7 hypothalamic GnRH neurons by induction of hyperpolarization of membrane potential

Junping Wen, Wenshan Lv, Jun Yang et al. · Biochemical and Biophysical Research Communications · 2008 · 132 citations

Membrane Potential, Neurophysiology, Medicine +12

Cryo-EM structure of TRPC5 at 2.8-Å resolution reveals unique and conserved structural elements essential for channel function

Jingjing Duan, Jian Li, Gui-Lan Chen et al. · Science Advances · 2019 · 114 citations · Full text

Hepatocyte Growth Factor Suppresses Proinflammatory NFκB Activation through GSK3β Inactivation in Renal Tubular Epithelial Cells

Rujun Gong, Abdalla Rifai, Yan Ge et al. · Journal of Biological Chemistry · 2008 · 97 citations · Full text

Renal Pathology, Immune Regulation, Renal Inflammation +23

GSK3β-mediated Keap1-independent regulation of Nrf2 antioxidant response: A molecular rheostat of acute kidney injury to chronic kidney disease transition

Minglei Lu, Pei Wang, Yingjin Qiao et al. · Redox Biology · 2019 · 94 citations · Full text

Lipid Peroxidation, Immunology, Renal Inflammation +26