A novel STAT3 inhibitor, S3I-201, attenuates renal interstitial fibroblast activation and interstitial fibrosis in obstructive nephropathy

Maoyin Pang, Li Ma, Rujun Gong, +7

Kidney International

InflammationGlomerulonephritisFibrosisUrologyRenal Function +12

Enhancer of Zeste Homolog 2 Inhibition Attenuates Renal Fibrosis by Maintaining Smad7 and Phosphatase and Tensin Homolog Expression

Xiaoxu Zhou, Xiujuan Zang, Murugavel Ponnusamy, +8

Journal of the American Society of Nephrology

Genetic or Pharmacologic Blockade of EGFR Inhibits Renal Fibrosis

Na Liu, Jian-Kan Guo, Maoyin Pang, +7

Journal of the American Society of Nephrology

Antifibrotic TherapyRenal PathologyRenal InflammationPathologyNephrology +24

The ketone body β-hydroxybutyrate mitigates the senescence response of glomerular podocytes to diabetic insults

Yudong Fang, Bohan Chen, Athena Y. Gong, +4

Kidney International

Metabolic SyndromeKetone BodyRenal FunctionMedicineDiabetic Insults +9

Sustained Activation of EGFR Triggers Renal Fibrogenesis after Acute Kidney Injury

Jinhua Tang, Na Liu, Evelyn Tolbert, +6

American Journal Of Pathology

FibrosisUrologyDevelopmental BiologyMedicineRenal Inflammation +8

Hepatocyte Growth Factor Ameliorates Renal Interstitial Inflammation in Rat Remnant Kidney by Modulating Tubular Expression of Macrophage Chemoattractant Protein-1 and RANTES

Rujun Gong, Abdalla Rifai, Evelyn Tolbert, +3

Journal of the American Society of Nephrology

Hepatocyte Growth Factor Suppresses Proinflammatory NFκB Activation through GSK3β Inactivation in Renal Tubular Epithelial Cells

Rujun Gong, Abdalla Rifai, Yan Ge, +2

Journal of Biological Chemistry

Renal PathologyImmune RegulationRenal InflammationImmunologyNfkappab Activity +21

Hepatocyte Growth Factor Modulates Matrix Metalloproteinases and Plasminogen Activator/Plasmin Proteolytic Pathways in Progressive Renal Interstitial Fibrosis

Rujun Gong, Abdalla Rifai, Evelyn Tolbert, +2

Journal of the American Society of Nephrology

Renal PathologyRenal InflammationPathologyCellular PhysiologyInflammation +21

Anti-Inflammatory Effect of Hepatocyte Growth Factor in Chronic Kidney Disease

Rujun Gong, Abdalla Rifai, Lance D. Dworkin

Journal of the American Society of Nephrology

ImmunologyRenal InflammationPathologyInflammationRenal Function +17

GSK3β-mediated Keap1-independent regulation of Nrf2 antioxidant response: A molecular rheostat of acute kidney injury to chronic kidney disease transition

Minglei Lu, Pei Wang, Yingjin Qiao, +7

Redox Biology

Lipid PeroxidationImmunologyRenal InflammationCell DeathNrf2 Antioxidant Response +24