A novel STAT3 inhibitor, S3I-201, attenuates renal interstitial fibroblast activation and interstitial fibrosis in obstructive nephropathy

Maoyin Pang, Li Ma, Rujun Gong, +7

Kidney International

InflammationGlomerulonephritisFibrosisUrologyRenal Function +12

Inhibition of histone deacetylase activity attenuates renal fibroblast activation and interstitial fibrosis in obstructive nephropathy

Maoyin Pang, Jagan Kothapally, Haiping Mao, +4

American Journal of Physiology-Renal Physiology

Enhancer of Zeste Homolog 2 Inhibition Attenuates Renal Fibrosis by Maintaining Smad7 and Phosphatase and Tensin Homolog Expression

Xiaoxu Zhou, Xiujuan Zang, Murugavel Ponnusamy, +8

Journal of the American Society of Nephrology

Genetic or Pharmacologic Blockade of EGFR Inhibits Renal Fibrosis

Na Liu, Jian-Kan Guo, Maoyin Pang, +7

Journal of the American Society of Nephrology

Antifibrotic TherapyRenal PathologyRenal InflammationPathologyNephrology +24

Blocking the Class I Histone Deacetylase Ameliorates Renal Fibrosis and Inhibits Renal Fibroblast Activation via Modulating TGF-Beta and EGFR Signaling

Na Liu, Song He, Li Ma, +7

PLoS ONE

Endogenous hepatocyte growth factor ameliorates chronic renal injury by activating matrix degradation pathways

Youhua Liu, Krupa Rajur, Evelyn Tolbert, +1

Kidney International

InflammationUrologyMatrix Degradation PathwaysHepatologyRenal Function +13

Up-regulation of hepatocyte growth factor receptor: An amplification and targeting mechanism for hepatocyte growth factor action in acute renal failure

Youhua Liu, Evelyn Tolbert, Lin Lin, +4

Kidney International

UrologyAcute Renal FailureHepatologyRenal FunctionMedicine +9

Sustained Activation of EGFR Triggers Renal Fibrogenesis after Acute Kidney Injury

Jinhua Tang, Na Liu, Evelyn Tolbert, +6

American Journal Of Pathology

FibrosisUrologyDevelopmental BiologyMedicineRenal Inflammation +8

Src inhibition blocks renal interstitial fibroblast activation and ameliorates renal fibrosis

Yanli Yan, Li Ma, Xiaoxu Zhou, +7

Kidney International

UrologyFibrosisRenal FunctionTumor MicroenvironmentMedicine +8

Calcium antagonists and converting enzyme inhibitors reduce renal injury by different mechanisms

Lance D. Dworkin, Judith A. Benstein, Miriam Parker, +2

Kidney International