Alexander N. Phillipou

Template-Hopping Approach Leads to Potent, Selective, and Highly Soluble Bromo and Extraterminal Domain (BET) Second Bromodomain (BD2) Inhibitors

Helen Aylott, Stephen J. Atkinson, Paul Bamborough et al. · Journal of Medicinal Chemistry · 2021 · 28 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +14

Optimization of a Series of 2,3-Dihydrobenzofurans as Highly Potent, Second Bromodomain (BD2)-Selective, Bromo and Extra-Terminal Domain (BET) Inhibitors

Simon C. C. Lucas, Stephen J. Atkinson, Chun‐wa Chung et al. · Journal of Medicinal Chemistry · 2021 · 25 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +15

Optimization of Potent ATAD2 and CECR2 Bromodomain Inhibitors with an Atypical Binding Mode

Simon C. C. Lucas, Stephen J. Atkinson, Paul Bamborough et al. · Journal of Medicinal Chemistry · 2020 · 22 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +16

Cellular Target Engagement Approaches to Monitor Epigenetic Reader Domain Interactions

Alexander N. Phillipou, Charles S. Lay, Charlotte E. Carver et al. · SLAS DISCOVERY · 2019 · 13 citations · Full text

Medicine, Molecular Biology, Pharmacology +13