Morphological screening of mesenchymal mammary tumor organoids to identify drugs that reverse epithelial-mesenchymal transition

Na Zhao, Reid T. Powell, Xueying Yuan, +10

Nature Communications

Histone H2A phosphorylation recruits topoisomerase <scp>II</scp> α to centromeres to safeguard genomic stability

Miao Zhang, Liang Cai, Qinfu Chen, +8

The EMBO Journal

Histone ModificationsChromatinTranscriptional RegulationChromosome DynamicsChromatin Structure +13

Bub1 and CENP-U redundantly recruit Plk1 to stabilize kinetochore-microtubule attachments and ensure accurate chromosome segregation

Qinfu Chen, Miao Zhang, Xuan Pan, +12

Cell Reports

Reactivation of Epstein-Barr Virus by HIF-1α Requires p53

Richard J. Kraus, Blue-leaf A. Cordes, Saraniya Sathiamoorthi, +7

Journal of Virology

Targeting eIF4A triggers an interferon response to synergize with chemotherapy and suppress triple-negative breast cancer

Na Zhao, Elena B. Kabotyanski, Alexander B. Saltzman, +18

Journal of Clinical Investigation

Breast OncologyImmunologyMrna TranslationZotatifin TreatmentImmunoediting +17

Aldosterone promotes renal interstitial fibrosis via the AIF‑1/AKT/mTOR signaling pathway

Xueying Yuan, Xingzhi Wang, Yushu Li, +3

Molecular Medicine Reports

Inflammatory Lung DiseaseLung InflammationRenal PathologyImmunologyRenal Inflammation +24

The gut microbiota contributes to the infection of bovine viral diarrhea virus in mice

Zecai Zhang, Jiang Huang, Chuang Li, +7

Journal of Virology

CREB-binding protein/P300 bromodomain inhibition reduces neutrophil accumulation and activates antitumor immunity in triple-negative breast cancer

Xueying Yuan, Xiaoxin Hao, Hilda L. Chan, +11

JCI Insight

Upregulation of allograft inflammatory factor‑1 expression and secretion by macrophages stimulated with aldosterone promotes renal fibroblasts to a profibrotic phenotype

Yushu Li, Xingzhi Wang, Lei Zhang, +4

International Journal of Molecular Medicine

Normal MacrophagesLung InflammationProfibrotic PhenotypeRenal PathologyImmunology +21

Elevated Soluble Podoplanin Associates with Hypercoagulability in Patients with Nephrotic Syndrome

Ying Ji, Yanli Wang, Fang Xu, +6

Clinical and Applied Thrombosis/Hemostasis