Magda Kosmopoulou

Cross-class metallo-β-lactamase inhibition by bisthiazolidines reveals multiple binding modes

Philip Hinchliffe, Mariano M. González, María F. Mojica et al. · Proceedings of the National Academy of Sciences · 2016 · 140 citations · Full text

Antimicrobial Chemotherapy, Free Thiol, Pharmaceutical Chemistry +18

Bisthiazolidines: A Substrate-Mimicking Scaffold as an Inhibitor of the NDM-1 Carbapenemase

Mariano M. González, Magda Kosmopoulou, María F. Mojica et al. · ACS Infectious Diseases · 2015 · 111 citations · Full text

Combinatorial Chemistry, Crystal Structure, Substrate-mimicking Scaffold +20

Crystal structure of an Aurora-A mutant that mimics Aurora-B bound to MLN8054: insights into selectivity and drug design

Charlotte A. Dodson, Magda Kosmopoulou, Mark W. Richards et al. · Biochemical Journal · 2010 · 97 citations · Full text

Kinetic and crystallographic studies on 2‐(β‐D‐glucopyranosyl)‐5‐methyl‐1, 3, 4‐oxadiazole, ‐benzothiazole, and ‐benzimidazole, inhibitors of muscle glycogen phosphorylase b. Evidence for a new binding site

Evangelia D. Chrysina, Magda Kosmopoulou, Constantinos Tiraidis et al. · Protein Science · 2005 · 86 citations · Full text

High Resolution, Glycobiology, Chemical Biology +20

Imidazo[4,5-<i>b</i>]pyridine Derivatives As Inhibitors of Aurora Kinases: Lead Optimization Studies toward the Identification of an Orally Bioavailable Preclinical Development Candidate

Vassilios Bavetsias, Jonathan M. Large, Chongbo Sun et al. · Journal of Medicinal Chemistry · 2010 · 81 citations · Full text