Concepedia

Angus E. Donald

AE

4

Publications

370

Citations

4

H-Index

1990

Active since

Affiliations

Merck & Co., Inc., Rahway, NJ, USA (United States)(Current)

Angus E. Donald is an author at Merck & Co., Inc., Rahway, NJ, USA (United States) specializing in neuropharmacology, pharmacotherapy, and medicine.

Top concepts

Publications per year

1990–1993

4

Publications

4

Kynurenic acid derivatives. Structure-activity relationships for excitatory amino acid antagonism and identification of potent and selective antagonists at the glycine site on the N-methyl-D-aspartate receptor

Paul D. Leeson, R. BAKER, Robert W. Carling et al. · Journal of Medicinal Chemistry · 1991 · 144 citations

Enantiomers of HA-966 (3-amino-1-hydroxypyrrolid-2-one) exhibit distinct central nervous system effects: (+)-HA-966 is a selective glycine/N-methyl-D-aspartate receptor antagonist, but (-)-HA-966 is a potent gamma-butyrolactone-like sedative.

L. Singh, Angus E. Donald, Alan C. Foster et al. · Proceedings of the National Academy of Sciences · 1990 · 136 citations · Full text

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Kynurenic acid analogues with improved affinity and selectivity for the glycine site on the N-methyl-D-aspartate receptor from rat brain.

Alan C. Foster, John A. Kemp, Paul D. Leeson et al. · Molecular Pharmacology · 1992 · 69 citations

Derivatives of 1-hydroxy-3-aminopyrrolidin-2-one (HA-966). Partial agonists at the glycine site of the NMDA receptor

Paul D. Leeson, Brian J. Williams, Michael Rowley et al. · Bioorganic & Medicinal Chemistry Letters · 1993 · 21 citations

, , +12

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