Kyron McAllister

Soluble and particulate Co‐Cr‐Mo alloy implant metals activate the inflammasome danger signaling pathway in human macrophages: A novel mechanism for implant debris reactivity

Marco S. Caicedo, Ronak Desai, Kyron McAllister et al. · Journal of Orthopaedic Research® · 2008 · 253 citations · Full text

Soluble ions more than particulate cobalt‐alloy implant debris induce monocyte costimulatory molecule expression and release of proinflammatory cytokines critical to metal‐induced lymphocyte reactivity

Marco S. Caicedo, P. Pennekamp, Kyron McAllister et al. · Journal of Biomedical Materials Research Part A · 2009 · 134 citations

Orthopedic implant cobalt‐alloy particles produce greater toxicity and inflammatory cytokines than titanium alloy and zirconium alloy‐based particles<i>in vitro</i>, in human osteoblasts, fibroblasts, and macrophages

Ali Dalal, V. D. Pawar, Kyron McAllister et al. · Journal of Biomedical Materials Research Part A · 2012 · 123 citations

Engineering, Immunology, Greater Toxicity +18

Increasing both CoCrMo‐alloy particle size and surface irregularity induces increased macrophage inflammasome activation in vitro potentially through lysosomal destabilization mechanisms

Marco S. Caicedo, Lauryn Samelko, Kyron McAllister et al. · Journal of Orthopaedic Research® · 2013 · 117 citations · Full text

Macrophage reactivity to different polymers demonstrates particle size‐ and material‐specific reactivity: PEEK‐OPTIMA^®particles versus UHMWPE particles in the submicron, micron, and 10 micron size ranges

Nadim J. Hallab, Kyron McAllister, Mark Brady et al. · Journal of Biomedical Materials Research Part B Applied Biomaterials · 2011 · 69 citations

Tissue Engineering, Macromolecular Chemistry, Engineering +31