Chen-Pin Hung

Discovery of an Oxycyclohexyl Acid Lysophosphatidic Acid Receptor 1 (LPA₁) Antagonist BMS-986278 for the Treatment of Pulmonary Fibrotic Diseases

Peter T. W. Cheng, Robert F. Kaltenbach, Hao Zhang et al. · Journal of Medicinal Chemistry · 2021 · 57 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +8

Discovery of 5-Chloro-4-((1-(5-chloropyrimidin-2-yl)piperidin-4-yl)oxy)-1-(2-fluoro-4-(methylsulfonyl)phenyl)pyridin-2(1<i>H</i>)-one (BMS-903452), an Antidiabetic Clinical Candidate Targeting GPR119

Dean A. Wacker, Ying Wang, Matthias Broekema et al. · Journal of Medicinal Chemistry · 2014 · 46 citations · Full text

Medicine, Medicinal Chemistry, Pharmacology +17

Discovery of ( <i>R</i> )-9-Ethyl-1,3,4,10b-tetrahydro-7-trifluoromethylpyrazino[2,1- <i>a</i> ]isoindol- 6(2 <i>H</i> )-one, a Selective, Orally Active Agonist of the 5-HT _2C Receptor

Dean A. Wacker, Jeffrey Varnes, Sarah E. Malmstrom et al. · Journal of Medicinal Chemistry · 2007 · 33 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +16

Tricyclic dihydroquinazolinones as novel 5-HT2C selective and orally efficacious anti-obesity agents

Saleem Ahmad, Khehyong Ngu, Keith J. Miller et al. · Bioorganic & Medicinal Chemistry Letters · 2009 · 20 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +11

Synthesis and SAR of potent and selective tetrahydropyrazinoisoquinolinone 5-HT2C receptor agonists

Guohua Zhao, Chet Kwon, Sharon N. Bisaha et al. · Bioorganic & Medicinal Chemistry Letters · 2013 · 15 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +12