Sachin Gajghate

Small Molecule Inhibitor of NRF2 Selectively Intervenes Therapeutic Resistance in KEAP1-Deficient NSCLC Tumors

Anju Singh, Sreedhar Venkannagari, Kyu Hee Oh et al. · ACS Chemical Biology · 2016 · 587 citations

Keap1-deficient Nsclc Tumors, Small Molecule Inhibitor, Cancer Biology +21

Exposure to Electronic Cigarettes Impairs Pulmonary Anti-Bacterial and Anti-Viral Defenses in a Mouse Model

Thomas E. Sussan, Sachin Gajghate, Rajesh K. Thimmulappa et al. · PLoS ONE · 2015 · 429 citations · Full text

Hyperglycemia-Driven Neuroinflammation Compromises BBB Leading to Memory Loss in Both Diabetes Mellitus (DM) Type 1 and Type 2 Mouse Models

Slava Rom, Viviana Zuluaga‐Ramirez, Sachin Gajghate et al. · Molecular Neurobiology · 2018 · 306 citations

Alzheimer's Disease, Medicine, Physiology +10

Hyperglycemia and advanced glycation end products disrupt BBB and promote occludin and claudin-5 protein secretion on extracellular microvesicles

Slava Rom, Nathan A. Heldt, Sachin Gajghate et al. · Scientific Reports · 2020 · 136 citations · Full text

miR-98 reduces endothelial dysfunction by protecting blood–brain barrier (BBB) and improves neurological outcomes in mouse ischemia/reperfusion stroke model

David L. Bernstein, Viviana Zuluaga‐Ramirez, Sachin Gajghate et al. · Journal of Cerebral Blood Flow & Metabolism · 2019 · 119 citations · Full text