G. C. Chan

Whole-genome sequencing reveals host factors underlying critical COVID-19

Athanasios Kousathanas, Erola Pairo‐Castineira, Konrad Rawlik et al. · Nature · 2022 · 347 citations · Full text

Life Sciences, Infectious Diseases, Molecular Genetics +17

Substitution mutational signatures in whole-genome–sequenced cancers in the UK population

Andrea Degasperi, Xueqing Zou, Tauanne Dias Amarante et al. · Science · 2022 · 284 citations · Full text

Life Sciences, Genetics, Oncology +14

Insights for precision oncology from the integration of genomic and clinical data of 13,880 tumors from the 100,000 Genomes Cancer Programme

Alona Sosinsky, John C. Ambrose, William Cross et al. · Nature Medicine · 2024 · 178 citations · Full text

Life Sciences, Genetics, Oncology +17

A systematic CRISPR screen defines mutational mechanisms underpinning signatures caused by replication errors and endogenous DNA damage

Xueqing Zou, Gene Ching Chiek Koh, Arjun S. Nanda et al. · Nature Cancer · 2021 · 165 citations · Full text

Life Sciences, Genetics, Molecular Biology +14

Origins and impact of extrachromosomal DNA

Chris Bailey, Oriol Pich, Kerstin Thol et al. · Nature · 2024 · 142 citations · Full text

Medicine, Genetics, Oncology +14