Chronic Reduction of GIP Secretion Alleviates Obesity and Insulin Resistance Under High-Fat Diet Conditions

Daniela Nasteska, Norio Harada, Kazuyo Suzuki, +7

Diabetes

NutritionChronic ReductionGlucose ToleranceHigh-fat Diet ConditionsInsulin Signaling +17

Free Fatty Acid Receptor GPR120 Is Highly Expressed in Enteroendocrine K Cells of the Upper Small Intestine and Has a Critical Role in GIP Secretion After Fat Ingestion

Kanako Iwasaki, Norio Harada, Kazuki Sasaki, +12

Endocrinology

Transcriptional Regulatory Factor X6 (Rfx6) Increases Gastric Inhibitory Polypeptide (GIP) Expression in Enteroendocrine K-cells and Is Involved in GIP Hypersecretion in High Fat Diet-induced Obesity

Kazuyo Suzuki, Norio Harada, Shunsuke Yamane, +10

Journal of Biological Chemistry

Inhibition of Gastric Inhibitory Polypeptide Receptor Signaling in Adipose Tissue Reduces Insulin Resistance and Hepatic Steatosis in High-Fat Diet–Fed Mice

Erina Joo, Norio Harada, Shunsuke Yamane, +9

Diabetes

Fatty acid-binding protein 5 regulates diet-induced obesity via GIP secretion from enteroendocrine K cells in response to fat ingestion

Kimitaka Shibue, Shunsuke Yamane, Norio Harada, +11

American Journal of Physiology-Endocrinology and Metabolism

γ-tocotrienol attenuates TNF-α-induced changes in secretion and gene expression of MCP-1, IL-6 and adiponectin in 3T3-L1 adipocytes

Tetsuro Matsunaga, AYAE SHOJI, Ning Gu, +7

Molecular Medicine Reports

3T3-l1 AdipocytesTnf-α-induced ChangesIl-6 SecretionImmunologyImmune Regulation +22

Chronic high-sucrose diet increases fibroblast growth factor 21 production and energy expenditure in mice

Ryuya Maekawa, Yusuke Seino, Hidetada Ogata, +11

The Journal of Nutritional Biochemistry

NutritionHuman GrowthEnergy ExpenditureSucrose IntakeOxidative Stress +23

Effects of glucose and meal ingestion on incretin secretion in Japanese subjects with normal glucose tolerance

Shunsuke Yamane, Norio Harada, Akihiro Hamasaki, +8

Journal of Diabetes Investigation

Distribution and hormonal characterization of primary murine L cells throughout the gastrointestinal tract

Kazuyo Suzuki, Kanako Iwasaki, Yuki Murata, +9

Journal of Diabetes Investigation

Plasma gastric inhibitory polypeptide and glucagon-like peptide-1 levels after glucose loading are associated with different factors in Japanese subjects

Norio Harada, Akihiro Hamasaki, Shunsuke Yamane, +4

Journal of Diabetes Investigation