Thomas W. Gero

Single and Dual Targeting of Mutant EGFR with an Allosteric Inhibitor

Ciric To, Jaebong Jang, Ting Chen et al. · Cancer Discovery · 2019 · 319 citations · Full text

Exploring Targeted Degradation Strategy for Oncogenic KRASG12C

Mei Zeng, Yuan Xiong, Nozhat Safaee et al. · Cell chemical biology · 2019 · 266 citations · Full text

Oncogenic Agent, Molecular Biology, Degradation Reaction +3

An allosteric inhibitor against the therapy-resistant mutant forms of EGFR in non-small cell lung cancer

Ciric To, Tyler S. Beyett, Jaebong Jang et al. · Nature Cancer · 2022 · 146 citations · Full text

Therapy-resistant Mutant Forms, Medicine, Pharmacology +9

Potent and Selective Covalent Quinazoline Inhibitors of KRAS G12C

Mei Zeng, Jia Lu, Lianbo Li et al. · Cell chemical biology · 2017 · 134 citations · Full text

Medicinal Chemistry, Kras G12c, Medicine +6

Discovery and Optimization of Dibenzodiazepinones as Allosteric Mutant-Selective EGFR Inhibitors

Dries J.H. De Clercq, David E. Heppner, Ciric To et al. · ACS Medicinal Chemistry Letters · 2019 · 87 citations · Full text