Keith A. Stubbs

A potent mechanism-inspired O-GlcNAcase inhibitor that blocks phosphorylation of tau in vivo

Scott A. Yuzwa, Matthew S. Macauley, Julia Heinonen et al. · Nature Chemical Biology · 2008 · 704 citations · Full text

Life Sciences, Biochemistry, Medicinal Chemistry +10

Perturbation of Indole-3-Butyric Acid Homeostasis by the UDP-Glucosyltransferase<i>UGT74E2</i>Modulates<i>Arabidopsis</i>Architecture and Water Stress Tolerance

Vanesa B. Tognetti, Olivier Van Aken, Kris Morreel et al. · The Plant Cell · 2010 · 488 citations · Full text

Life Sciences, Plant Biology, Plant Sciences +17

Structure and mechanism of a bacterial β-glucosaminidase having O-GlcNAcase activity

Rebecca J. Dennis, Edward J. Taylor, Matthew S. Macauley et al. · Nature Structural & Molecular Biology · 2006 · 191 citations

Life Sciences, Biochemistry, Microbiology +12

Carrageenan catabolism is encoded by a complex regulon in marine heterotrophic bacteria

Elizabeth Ficko‐Blean, Aurélie Préchoux, François Thomas et al. · Nature Communications · 2017 · 174 citations · Full text

Life Sciences, Biology, Microbiology +17

Analysis of PUGNAc and NAG-thiazoline as Transition State Analogues for Human <i>O</i>-GlcNAcase:  Mechanistic and Structural Insights into Inhibitor Selectivity and Transition State Poise

Garrett E. Whitworth, Matthew S. Macauley, Keith A. Stubbs et al. · Journal of the American Chemical Society · 2006 · 163 citations · Full text

Life Sciences, Biochemistry, Pharmacology +17