Alexander Sumaroka

Human gene therapy for RPE65 isomerase deficiency activates the retinoid cycle of vision but with slow rod kinetics

Artur V. Cideciyan, Tomás S. Alemán, Sanford L. Boye et al. · Proceedings of the National Academy of Sciences · 2008 · 660 citations · Full text

Slow Rod Kinetics, Gene Therapies, Ocular Disease +12

Human retinal gene therapy for Leber congenital amaurosis shows advancing retinal degeneration despite enduring visual improvement

Artur V. Cideciyan, Samuel G. Jacobson, William A. Beltran et al. · Proceedings of the National Academy of Sciences · 2013 · 436 citations · Full text

Improvement and Decline in Vision with Gene Therapy in Childhood Blindness

Samuel G. Jacobson, Artur V. Cideciyan, Alejandro J. Román et al. · New England Journal of Medicine · 2015 · 373 citations · Full text

Ocular Disease, Genetics, Optogenetics +19

Human <i>RPE65</i> Gene Therapy for Leber Congenital Amaurosis: Persistence of Early Visual Improvements and Safety at 1 Year

Artur V. Cideciyan, William W. Hauswirth, Tomás S. Alemán et al. · Human Gene Therapy · 2009 · 311 citations · Full text

Probing Mechanisms of Photoreceptor Degeneration in a New Mouse Model of the Common Form of Autosomal Dominant Retinitis Pigmentosa due to P23H Opsin Mutations

Sanae Sakami, Tadao Maeda, Grzegorz Bereta et al. · Journal of Biological Chemistry · 2011 · 294 citations · Full text