Stephen P. Keen

Enantioselective Synthesis of 4′-Ethynyl-2-fluoro-2′-deoxyadenosine (EFdA) via Enzymatic Desymmetrization

Mark McLaughlin, Jongrock Kong, Kevin M. Belyk et al. · Organic Letters · 2017 · 68 citations

Natural Sciences, Chemistry, Medicinal Chemistry +16

Development of a Fit-for-Purpose Large-Scale Synthesis of an Oral PARP Inhibitor

Debra J. Wallace, Carl A. Baxter, Karel J. M. Brands et al. · Organic Process Research & Development · 2011 · 56 citations

Pharmacy, Medicinal Chemistry, Pharmacology +13

Practical Asymmetric Synthesis of a γ-Secretase Inhibitor Exploiting Substrate-Controlled Intramolecular Nitrile Oxide−Olefin Cycloaddition

Jeremy P. Scott, Steven F. Oliver, Karel M. J. Brands et al. · The Journal of Organic Chemistry · 2006 · 53 citations

Pharmacy, Medicinal Chemistry, Pharmacology +14

Stereoselective Total Syntheses and Reassignment of Stereochemistry of the Freshwater Cyanobacterial Hepatotoxins Cylindrospermopsin and 7-Epicylindrospermopsin

Geoffrey R. Heintzelman, Wen-Kui Fang, Stephen P. Keen et al. · Journal of the American Chemical Society · 2002 · 53 citations

Natural Sciences, Chemistry, Bioorganic Chemistry +12

Multikilogram-Scale Synthesis of a Chiral Cyclopropanol and an Investigation of the Safe Use of Lithium Acetylide–Ethylene Diamine Complex

Ephraim M. Bassan, Carl A. Baxter, Gregory L. Beutner et al. · Organic Process Research & Development · 2011 · 49 citations

Natural Sciences, Chemistry, Biocatalysis +12