Mihaela‐Olivia Dobrica

Lettuce‐produced hepatitis C virus E1E2 heterodimer triggers immune responses in mice and antibody production after oral vaccination

Jihong Liu Clarke, Lisa Paruch, Mihaela‐Olivia Dobrica et al. · Plant Biotechnology Journal · 2017 · 63 citations · Full text

A novel chimeric Hepatitis B virus S/preS1 antigen produced in mammalian and plant cells elicits stronger humoral and cellular immune response than the standard vaccine-constituent, S protein

Mihaela‐Olivia Dobrica, Catalin Lazar, Lisa Paruch et al. · Antiviral Research · 2017 · 23 citations

Vaccination, Viral Hepatitis, Medicine +12

Oral administration of a chimeric Hepatitis B Virus S/preS1 antigen produced in lettuce triggers infection neutralizing antibodies in mice

Mihaela‐Olivia Dobrica, Catalin Lazar, Lisa Paruch et al. · Vaccine · 2018 · 19 citations

Vaccination, Mucosal Vaccination, Viral Hepatitis +10

The “humanized” N‐glycosylation pathway in <scp>CRISPR</scp>/Cas9‐edited <i>Nicotiana benthamiana</i> significantly enhances the immunogenicity of a S/<scp>preS1</scp> Hepatitis B Virus antigen and the virus‐neutralizing antibody response in vaccinated mice

Ana‐Maria Pantazica, André van Eerde, Mihaela‐Olivia Dobrica et al. · Plant Biotechnology Journal · 2023 · 18 citations · Full text

Hepatitis C virus E2 envelope glycoprotein produced in <i>Nicotiana benthamiana</i> triggers humoral response with virus‐neutralizing activity in vaccinated mice

Mihaela‐Olivia Dobrica, André van Eerde, Cătălin Ţucureanu et al. · Plant Biotechnology Journal · 2021 · 15 citations · Full text

Viral Replication, Engineering, Nicotiana Benthamiana +21