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A novel chimeric Hepatitis B virus S/preS1 antigen produced in mammalian and plant cells elicits stronger humoral and cellular immune response than the standard vaccine-constituent, S protein

VaccinationViral HepatitisMedicineVaccine TargetImmunologyPlant CellsHepatitisVirologyS ProteinHumoral ResponseHumoral ImmunityAntiviral ResponseVaccine DesignStandard Vaccine-constituentViral Immunity