Microbiota regulate innate immune signaling and protective immunity against cancer

Changsheng Xing, Mingjun Wang, Adebusola Alagbala Ajibade, +13

Cell Host & Microbe

DysbiosisInnate Immune SystemImmunologyGut-organ AxisInnate Immunity +6

Pharmacological inhibition of fatty acid synthesis blocks SARS-CoV-2 replication

Junjun Chu, Changsheng Xing, Yang Du, +10

Nature Metabolism

Cross-Regulation of Two Type I Interferon Signaling Pathways in Plasmacytoid Dendritic Cells Controls Anti-malaria Immunity and Host Mortality

Xiao Yu, Baowei Cai, Mingjun Wang, +10

Immunity

InflammationHost MortalityInnate Immune SystemImmunologyImmunologic Mechanism +6

KLF5 Activates MicroRNA 200 Transcription To Maintain Epithelial Characteristics and Prevent Induced Epithelial-Mesenchymal Transition in Epithelial Cells

Baotong Zhang, Zhiqian Zhang, Siyuan Xia, +9

Molecular and Cellular Biology

Prevents EmtTumor BiologyEpithelial-mesenchymal TransitionTranscriptional RegulationMolecular Emt Properties +14

Assembly of the WHIP-TRIM14-PPP6C Mitochondrial Complex Promotes RIG-I-Mediated Antiviral Signaling

Peng Tan, Lian He, Jun Cui, +9

Molecular Cell

Signal TransductionMitochondrial FunctionMitochondrial DynamicNatural SciencesMolecular Biology +6

Single-cell transcriptomics of adult macaque hippocampus reveals neural precursor cell populations

Zhao-Zhe Hao, Jia-Ru Wei, Dongchang Xiao, +12

Nature Neuroscience

Developmental BiologyMolecular NeuroscienceNeurogenomicsAdult Macaque HippocampusCellular Neuroscience +11

Inflammasome activation negatively regulates MyD88-IRF7 type I IFN signaling and anti-malaria immunity

Xiao Yu, Yang Du, Chunmei Cai, +11

Nature Communications

Atbf1 Regulates Pubertal Mammary Gland Development Likely by Inhibiting the Pro-Proliferative Function of Estrogen-ER Signaling

Mei Li, Xiaoying Fu, Gui Ma, +6

PLoS ONE

Breast OncologyEstrogen ReceptorGynecologyCell DifferentiationReproductive Biology +18

Myeloid loss of Beclin 1 promotes PD-L1hi precursor B cell lymphoma development

Peng Tan, Lian He, Changsheng Xing, +9

Journal of Clinical Investigation

Development of a TCR-like antibody and chimeric antigen receptor against NY-ESO-1/HLA-A2 for cancer immunotherapy

Xin Liu, Yixiang Xu, Wei Xiong, +12

Journal for ImmunoTherapy of Cancer