Prevention of Dietary-Fat-Fueled Ketogenesis Attenuates BRAF V600E Tumor Growth

Siyuan Xia, Ruiting Lin, Lingtao Jin, +25

Cell Metabolism

Chemoprevention StrategyCancer PreventionBreast CancerMedicineCell Biology +3

Acetylation of KLF5 maintains EMT and tumorigenicity to cause chemoresistant bone metastasis in prostate cancer

Baotong Zhang, Yixiang Li, Qiao Wu, +19

Nature Communications

Trans-vaccenic acid reprograms CD8+ T cells and anti-tumour immunity

Hao Fan, Siyuan Xia, Junhong Xiang, +40

Nature

Tetrameric Acetyl-CoA Acetyltransferase 1 Is Important for Tumor Growth

Jun Fan, Ruiting Lin, Siyuan Xia, +27

Molecular Cell

MedicineTumor GrowthCancer BiologyCell BiologyCancer Research +2

KLF5 Activates MicroRNA 200 Transcription To Maintain Epithelial Characteristics and Prevent Induced Epithelial-Mesenchymal Transition in Epithelial Cells

Baotong Zhang, Zhiqian Zhang, Siyuan Xia, +9

Molecular and Cellular Biology

Prevents EmtTumor BiologyEpithelial-mesenchymal TransitionTranscriptional RegulationMolecular Emt Properties +14

γ-6-Phosphogluconolactone, a Byproduct of the Oxidative Pentose Phosphate Pathway, Contributes to AMPK Activation through Inhibition of PP2A

Xue Gao, Liang Zhao, Shuangping Liu, +18

Molecular Cell

BiosynthesisSignal TransductionMolecular PhysiologyBiochemistryCellular Enzymology +7

Regulatory Role of Vγ1 γδ T Cells in Tumor Immunity through IL-4 Production

Jianlei Hao, Siyuan Dong, Siyuan Xia, +11

The Journal of Immunology

Adaptive Immune SystemT-regulatory CellImmune RegulationImmunologyImmunologic Mechanism +21

High susceptibility to liver injury in IL-27 p28 conditional knockout mice involves intrinsic interferon-γ dysregulation of CD4+ T cells

Song Zhang, Ruifang Liang, Wei Luo, +22

Hepatology

TGF-β causes Docetaxel resistance in Prostate Cancer via the induction of Bcl-2 by acetylated KLF5 and Protein Stabilization

Yixiang Li, Baotong Zhang, Lingwei Xiang, +5

Theranostics

Targeting 6-phosphogluconate dehydrogenase in the oxidative PPP sensitizes leukemia cells to antimalarial agent dihydroartemisinin

Shannon Elf, Richard Z. Lin, Siyuan Xia, +12

Oncogene

Oxidative PppBiochemistryAntiparasitic AgentMedicineLeukemia Cells +6