Concepedia

Nickolas Tsakmaklis

NT

8

Publications

554

Citations

8

H-Index

2014

Active since

Affiliations

Harvard University(Current)

Dana-Farber Cancer Institute

Memorial Sloan Kettering Cancer Center

Boston University

Nickolas Tsakmaklis is an author at Harvard University specializing in cell signaling, immunology, and medicine.

Top concepts

Publications per year

2014–2022

8

Publications

8

The WHIM-like CXCR4S338X somatic mutation activates AKT and ERK, and promotes resistance to ibrutinib and other agents used in the treatment of Waldenstrom’s Macroglobulinemia

Yang Cao, Zachary R. Hunter, Xingguang Liu et al. · Leukemia · 2014 · 231 citations

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<i><scp>CXCR</scp>4 </i><scp>WHIM</scp>‐like frameshift and nonsense mutations promote ibrutinib resistance but do not supplant <i><scp>MYD</scp>88</i><sup>L265P</sup>‐directed survival signalling in <scp>W</scp>aldenström macroglobulinaemia cells

Yang Cao, Zachary R. Hunter, Xia Liu et al. · British Journal of Haematology · 2014 · 106 citations · Full text

Insights into the genomic landscape of MYD88 wild-type Waldenström macroglobulinemia

Zachary R. Hunter, Lian Xu, Nickolas Tsakmaklis et al. · Blood Advances · 2018 · 89 citations · Full text

SYK is activated by mutated MYD88 and drives pro-survival signaling in MYD88 driven B-cell lymphomas

Manit Munshi, Xia Liu, Jiaji G. Chen et al. · Blood Cancer Journal · 2020 · 44 citations · Full text

Genomic evolution of ibrutinib‐resistant clones in Waldenström macroglobulinaemia

Cristina Jiménez, Gloria Chan, Lian Xu et al. · British Journal of Haematology · 2020 · 33 citations · Full text

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