Ferrostatins Inhibit Oxidative Lipid Damage and Cell Death in Diverse Disease Models

Rachid Skouta, Scott J. Dixon, Jianlin Wang, +7

Journal of the American Chemical Society

OxysterolBiochemistryMedicineLipid PeroxidationApoptosis +12

A Small Molecule That Inhibits OGT Activity in Cells

Rodrigo F. Ortiz‐Meoz, Jiaoyang Jiang, Michael B. Lazarus, +7

ACS Chemical Biology

GlycobiologyMolecular BiologyChemical BiologyCellular PhysiologyCell Regulation +18

<i>O</i>-GlcNAc Transferase Recognizes Protein Substrates Using an Asparagine Ladder in the Tetratricopeptide Repeat (TPR) Superhelix

Zebulon G. Levine, Chenguang Fan, Michael S. Melicher, +3

Journal of the American Chemical Society

Protein ChemistryProtein ExpressionTetratricopeptide RepeatBiochemistryG Protein-coupled Receptor +12

Structure-Guided Identification of a Small Molecule That Inhibits Anaerobic Choline Metabolism by Human Gut Bacteria

Marina Orman, Smaranda Bodea, Michael A. Funk, +4

Journal of the American Chemical Society

DysbiosisCutc InhibitorGut-organ AxisMetabolic Pathway AnalysisIntestinal Microbiota +15

Discovery of a Cyclic Choline Analog That Inhibits Anaerobic Choline Metabolism by Human Gut Bacteria

Maud Bollenbach, Manuel A. Ortega, Marina Orman, +2

ACS Medicinal Chemistry Letters

Metal binding and interdomain thermodynamics of mammalian metallothionein-3: enthalpically favoured Cu⁺supplants entropically favoured Zn²⁺to form Cu₄⁺clusters under physiological conditions

Matthew R. Mehlenbacher, Rahma Elsiesy, Rabina Lakha, +6

Chemical Science

An alkane monooxygenase (AlkB) family in which all electron transfer partners are covalently bound to the oxygen-activating hydroxylase

Shoshana C. Williams, Dahlia Luongo, Marina Orman, +2

Journal of Inorganic Biochemistry

Aldehyde DehydrogenaseBiochemistryNatural SciencesMedicineEnzyme Catalysis +8

Experimental and Computational Mechanistic Investigation of Chlorocarbene Additions to Bridgehead Carbene–Anti-Bredt Systems: Noradamantylcarbene–Adamantene and Adamantylcarbene–Homoadamantene

Stephanie R. Hare, Marina Orman, Faizunnahar Dewan, +12

The Journal of Organic Chemistry

Materials ScienceChemical EngineeringEngineeringCarbene–anti-bredt SystemsPhotochemistry +9

Alterations to the broad-spectrum formin inhibitor SMIFH2 modulate potency but not specificity

Marina Orman, Maya Landis, Aisha Oza, +12

Scientific Reports