Jonathan T. Smith

A genomic mutational constraint map using variation in 76,156 human genomes

Siwei Chen, Laurent C. Francioli, Julia K. Goodrich et al. · Nature · 2023 · 1.1K citations · Full text

Medicine, Genetics, Evolutionary Biology +8

Biomimetic anisotropic polymeric nanoparticles coated with red blood cell membranes for enhanced circulation and toxin removal

Elana Ben‐Akiva, Randall A. Meyer, Hongzhe Yu et al. · Science Advances · 2020 · 236 citations · Full text

Nanoparticles, Tissue Engineering, Anisotropic Shape +20

Repeat expansions confer WRN dependence in microsatellite-unstable cancers

Niek van Wietmarschen, Sriram Sridharan, William J. Nathan et al. · Nature · 2020 · 182 citations · Full text

Tumor Heterogeneity, Genetics, Cancer Genomics +4

High-throughput RNA isoform sequencing using programmed cDNA concatenation

Aziz Al’Khafaji, Jonathan T. Smith, Kiran Garimella et al. · Nature Biotechnology · 2023 · 157 citations · Full text

Functional Genomics, Genetics, Rna Structure Prediction +6

Inferring compound heterozygosity from large-scale exome sequencing data

Michael H. Guo, Laurent C. Francioli, Sarah L. Stenton et al. · Nature Genetics · 2023 · 30 citations · Full text

Sequencing, Functional Genomics, Next-generation Sequencing +7