Muthukumaran Sivashanmugam

Virtual screening, molecular dynamics, and binding free energy calculations on human carbonic anhydrase IX catalytic domain for deciphering potential leads

Arun John, Muthukumaran Sivashanmugam, Umashankar Vetrivel et al. · Journal of Biomolecular Structure and Dynamics · 2016 · 32 citations

Virtual screening of natural inhibitors targeting ornithine decarboxylase with pharmacophore scaffolding of DFMO and validation by molecular dynamics simulation studies

Muthukumaran Sivashanmugam, K.N. Sulochana · Journal of Biomolecular Structure and Dynamics · 2018 · 27 citations

Drug Target, Dfmo Scaffold, Natural Inhibitors +16

Detection of novel coupled mutations in the katG gene (His276Met, Gln295His and Ser315Thr) in a multidrug-resistant Mycobacterium tuberculosis strain from Chennai, India, and insight into the molecular mechanism of isoniazid resistance using structural bioinformatics approaches

Gayathri Ramasubban, K. Lily Therese, Umashankar Vetrivel et al. · International Journal of Antimicrobial Agents · 2011 · 16 citations

Structural Bioinformatics Approaches, Pulmonary Tuberculosis, Katg Gene +14

Understanding variable disease severity in X-linked retinoschisis: Does RS1 secretory mechanism determine disease severity?

Dhandayuthapani Sudha, Srividya Neriyanuri, Ramya Sachidanandam et al. · PLoS ONE · 2018 · 15 citations · Full text

Ocular Disease, Photoreceptor Cell, Disease Mechanism +15

Computational modeling of novel inhibitory peptides targeting proteoglycan like region of carbonic anhydrase IX and <i>in vitro</i> validation in HeLa cells

Arun John, Muthukumaran Sivashanmugam, Sulochana Konerirajapuram Natarajan et al. · Journal of Biomolecular Structure and Dynamics · 2019 · 15 citations