K. Roempke

Influence of 16α,17α-acetal substitution and steroid nucleus fluorination on the topical to systemic activity ratio of glucocorticoids

Ralph Brattsand, A Thalén, K. Roempke et al. · Journal of Steroid Biochemistry · 1982 · 133 citations

Systemic Activity Ratio, Medicine, 16α,17α-Acetal Substitution +6

Correlation between chemical structure, receptor binding, and biological activity of some novel, highly active, 16 alpha, 17 alpha-acetal-substituted glucocorticoids.

Erik Dahlberg, A Thalén, Ralph Brattsand et al. · Molecular Pharmacology · 1984 · 130 citations

Ropivacaine Inhibits Leukocyte Rolling, Adhesion and CD11b/CD18 Expression

Titti Martinsson, Takaharu Oda, Eva Fernvik et al. · Journal of Pharmacology and Experimental Therapeutics · 1997 · 64 citations

Development of new glucocorticosteroids with a very high ratio between topical and systemic activities.

Ralph Brattsand, A Thalén, K. Roempke et al. · PubMed · 1982 · 63 citations

Inflammation, Medicinal Chemistry, Anti-inflammatory +14

A rat model for testing anti-inflammatory action in lung and the effect of glucocorticosteroids (GCS) in this model

L. Källström, R. Brattsand, Ulf Lövgren et al. · Inflammation Research · 1986 · 19 citations

Asthma, Inflammation, Anti-inflammatory Action +12