Steven S. Good

Metabolism of 5-fluorocytosine to 5-fluorouracil in human colorectal tumor cells transduced with the cytosine deaminase gene: significant antitumor effects when only a small percentage of tumor cells express cytosine deaminase.

Brian E. Huber, Elizabeth A. Austin, C A Richards et al. · Proceedings of the National Academy of Sciences · 1994 · 420 citations · Full text

Cytosine Deaminase, Immunology, Cancer Biology +18

1592U89, a novel carbocyclic nucleoside analog with potent, selective anti-human immunodeficiency virus activity

Susan M. Daluge, Steven S. Good, M B Faletto et al. · Antimicrobial Agents and Chemotherapy · 1997 · 384 citations · Full text

Immunology, Pharmacotherapy, Antiviral Drug +18

Potent and Selective Inhibition of Human Cytomegalovirus Replication by 1263W94, a Benzimidazole <scp>l</scp> -Riboside with a Unique Mode of Action

Karen K. Biron, Richard J. Harvey, Stanley C. Chamberlain et al. · Antimicrobial Agents and Chemotherapy · 2002 · 361 citations · Full text

Viral Replication, Unique Mode, Molecular Biology +18

In vivo antitumor activity of 5-fluorocytosine on human colorectal carcinoma cells genetically modified to express cytosine deaminase.

Brian E. Huber, Elizabeth A. Austin, Steven S. Good et al. · PubMed · 1993 · 230 citations

Widr Cells, Cytosine Deaminase, Chemoprevention Strategy +15

Unique intracellular activation of the potent anti-human immunodeficiency virus agent 1592U89

M B Faletto, Wayne H. Miller, Edward P. Garvey et al. · Antimicrobial Agents and Chemotherapy · 1997 · 222 citations · Full text

Immunology, Antiviral Drug, Immunotherapy +17