Steven S. Good

Metabolism of 5-fluorocytosine to 5-fluorouracil in human colorectal tumor cells transduced with the cytosine deaminase gene: significant antitumor effects when only a small percentage of tumor cells express cytosine deaminase.

Brian E. Huber, Elizabeth A. Austin, C A Richards et al. · Proceedings of the National Academy of Sciences · 1994 · 422 citations

Medicine, Oncology, Pharmacology +17

1592U89, a novel carbocyclic nucleoside analog with potent, selective anti-human immunodeficiency virus activity

Susan M. Daluge, Steven S. Good, M B Faletto et al. · Antimicrobial Agents and Chemotherapy · 1997 · 385 citations · Full text

Medicine, Medicinal Chemistry, Pharmacology +15

Potent and Selective Inhibition of Human Cytomegalovirus Replication by 1263W94, a Benzimidazole <scp>l</scp> -Riboside with a Unique Mode of Action

Karen K. Biron, Stanley C. Chamberlain, Steven S. Good et al. · Antimicrobial Agents and Chemotherapy · 2002 · 364 citations · Full text

Life Sciences, Medicinal Chemistry, Pharmacology +17

In vivo antitumor activity of 5-fluorocytosine on human colorectal carcinoma cells genetically modified to express cytosine deaminase.

Brian E. Huber, Elizabeth A. Austin, Steven S. Good et al. · PubMed · 1993 · 230 citations

Medicine, Oncology, Pharmacology +13

Unique intracellular activation of the potent anti-human immunodeficiency virus agent 1592U89

M B Faletto, Wayne H. Miller, Edward P. Garvey et al. · Antimicrobial Agents and Chemotherapy · 1997 · 225 citations · Full text

Life Sciences, Molecular Biology, Pharmacology +15