Cancer cell–autonomous contribution of type I interferon signaling to the efficacy of chemotherapy

Antonella Sistigu, Takahiro Yamazaki, Erika Vacchelli, +48

Nature Medicine

Cancer ImmunosurveillanceMedicineImmunologyTumor ImmunityCancer Cell Biology +6

Chemotherapy-induced antitumor immunity requires formyl peptide receptor 1

Erika Vacchelli, Yuting Ma, Elisa Elena Baracco, +39

Science

An Immunosurveillance Mechanism Controls Cancer Cell Ploidy

Laura Senovilla, Ilio Vitale, Isabelle Martins, +42

Science

Cyclophosphamide Synergizes with Type I Interferons through Systemic Dendritic Cell Reactivation and Induction of Immunogenic Tumor Apoptosis

Giovanna Schiavoni, Antonella Sistigu, Mara Valentini, +10

Cancer Research

Cyclophosphamide SynergizesDendritic CellImmunologyImmune RegulationPathology +20

Defective immunogenic cell death of HMGB1-deficient tumors: compensatory therapy with TLR4 agonists

Takahiro Yamazaki, Dalil Hannani, Vichnou Poirier-Colame, +11

Cell Death and Differentiation

Tumor BiologyCompensatory TherapyCancer ImmunosurveillanceMedicineTlr4 Agonists +12

IL-33 restricts tumor growth and inhibits pulmonary metastasis in melanoma-bearing mice through eosinophils

Valeria Lucarini, Giovanna Ziccheddu, Iole Macchia, +12

OncoImmunology

CCL2/CCR2-Dependent Recruitment of Functional Antigen-Presenting Cells into Tumors upon Chemotherapy

Yuting Ma, Stephen R. Mattarollo, Sandy Adjemian, +15

Cancer Research

Type I IFNs Control Antigen Retention and Survival of CD8α+ Dendritic Cells after Uptake of Tumor Apoptotic Cells Leading to Cross-Priming

Silvia Lorenzi, Fabrizio Mattei, Antonella Sistigu, +7

The Journal of Immunology

Adaptive Immune SystemImmunologyImmune RegulationCell DeathImmunodominance +21

Type I IFNs promote cancer cell stemness by triggering the epigenetic regulator KDM1B

Martina Musella, Andrea Guarracino, Nicoletta Manduca, +40

Nature Immunology

CHK1-targeted therapy to deplete DNA replication-stressed, p53-deficient, hyperdiploid colorectal cancer stem cells

Gwenola Manic, Michele Signore, Antonella Sistigu, +23

Gut