James A. Fraser

MCC950 directly targets the NLRP3 ATP-hydrolysis motif for inflammasome inhibition

Rebecca C. Coll, James R. Hill, Christopher J. Day et al. · Nature Chemical Biology · 2019 · 931 citations · Full text

Inflammation, Nlrp3 Atp-hydrolysis Motif, Anti-inflammatory +11

Complex multi-enhancer contacts captured by genome architecture mapping

Robert A. Beagrie, Antonio Scialdone, Markus Schueler et al. · Nature · 2017 · 733 citations · Full text

Functional Genomics, Genetics, Genomic Mechanism +6

The Genome of the Basidiomycetous Yeast and Human Pathogen <i>Cryptococcus neoformans</i>

Brendan Loftus, Eula Fung, Paola Roncaglia et al. · Science · 2005 · 724 citations

Biology, Basidiomycetous Yeast, Functional Genomics +14

Complexity of chromatin folding is captured by the strings and binders switch model

Mariano Barbieri, Mita Chotalia, James A. Fraser et al. · Proceedings of the National Academy of Sciences · 2012 · 623 citations · Full text

Genetics, Molecular Biology, Chromatin Folding Conformations +22

Whole‐genome sequencing identifies EN1 as a determinant of bone density and fracture

Hou‐Feng Zheng, Vincenzo Forgetta, Yi‐Hsiang Hsu et al. · Nature · 2015 · 616 citations · Full text

Bone Disease, Bone Health, Fracture Diagnostics +10