Feng Wang

Control of CCND1 ubiquitylation by the catalytic SAGA subunit USP22 is essential for cell cycle progression through G1 in cancer cells

Victoria Gennaro, Timothy J. Stanek, Amy R. Peck et al. · Proceedings of the National Academy of Sciences · 2018 · 125 citations · Full text

Life Sciences, Cell Biology, Molecular Biology +17

Ubiquitin-specific Protease-7 Inhibition Impairs Tip60-dependent Foxp3 + T-regulatory Cell Function and Promotes Antitumor Immunity

Liqing Wang, Suresh Kumar, Satinder Dahiya et al. · EBioMedicine · 2016 · 114 citations · Full text

Life Sciences, Immunology, Oncology +15

USP7-Specific Inhibitors Target and Modify the Enzyme's Active Site via Distinct Chemical Mechanisms

Alexandra Pozhidaeva, Gabrielle J. Valles, Feng Wang et al. · Cell chemical biology · 2017 · 105 citations · Full text

Life Sciences, Biochemistry, Pharmacology +16

USP7 Cooperates with NOTCH1 to Drive the Oncogenic Transcriptional Program in T-Cell Leukemia

Carlos A. Martínez, Kelly M. Arcipowski, Yixing Zhu et al. · Clinical Cancer Research · 2018 · 93 citations · Full text

Medicine, Cancer Biology, Oncology +15

Active site-targeted covalent irreversible inhibitors of USP7 impair the functions of Foxp3+ T-regulatory cells by promoting ubiquitination of Tip60

Feng Wang, Liqing Wang, Jian Wu et al. · PLoS ONE · 2017 · 53 citations · Full text

Medicine, Oncology, Pharmacology +17