Concepedia

Patrick A. Holt

PA

Statistics

Publications

6

Citations

411

H-Index

6

Active since

2008

Affiliations

University of Louisville(Current)

James Graham Brown Foundation

Patrick A. Holt is an author at University of Louisville specializing in structural biology, drug discovery, and dna replication.

Top concepts

Publications per year

2008–2013

6

Publications

6

Molecular Docking of Intercalators and Groove-Binders to Nucleic Acids Using Autodock and Surflex

Patrick A. Holt, Jonathan B. Chaires, John O. Trent · Journal of Chemical Information and Modeling · 2008 · 220 citations · Full text

Not all G-quadruplexes are created equally: an investigation of the structural polymorphism of the c-Myc G-quadruplex-forming sequence and its interaction with the porphyrin TMPyP4

Huy T. Le, M. Clarke Miller, Robert Buscaglia et al. · Organic & Biomolecular Chemistry · 2012 · 64 citations

Discovery of novel triple helical DNA intercalators by an integrated virtual and actual screening platform

Patrick A. Holt, Patricia A. Ragazzon, Lucjan Strękowski et al. · Nucleic Acids Research · 2009 · 40 citations · Full text

Polymorphism and resolution of oncogene promoter quadruplex-forming sequences

M. Clarke Miller, Huy T. Le, William L. Dean et al. · Organic & Biomolecular Chemistry · 2011 · 38 citations

A discovery funnel for nucleic acid binding drug candidates

Patrick A. Holt, Robert Buscaglia, John O. Trent et al. · Drug Development Research · 2010 · 25 citations · Full text

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