Thomas W. Corcoran

A Novel, Potent Dual Inhibitor of the Leukocyte Proteases Cathepsin G and Chymase

Lawrence de Garavilla, Michael N. Greco, N. Sukumar et al. · Journal of Biological Chemistry · 2005 · 93 citations · Full text

Life Sciences, Biochemistry, Medicinal Chemistry +17

Potent, Small-Molecule Inhibitors of Human Mast Cell Tryptase. Antiasthmatic Action of a Dipeptide-Based Transition-State Analogue Containing a Benzothiazole Ketone

Michael J. Costanzo, Stephen C. Yabut, Harold R. Almond et al. · Journal of Medicinal Chemistry · 2003 · 82 citations · Full text

Life Sciences, Medicinal Chemistry, Pharmacology +14

In-Depth Study of Tripeptide-Based α-Ketoheterocycles as Inhibitors of Thrombin. Effective Utilization of the S₁‘ Subsite and Its Implications to Structure-Based Drug Design

Michael J. Costanzo, Harold R. Almond, Leonard R. Hecker et al. · Journal of Medicinal Chemistry · 2004 · 67 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +13

Discovery of Potent, Selective, Orally Active, Nonpeptide Inhibitors of Human Mast Cell Chymase

Michael N. Greco, Michael Hawkins, Eugene T. Powell et al. · Journal of Medicinal Chemistry · 2007 · 59 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +15

Nonpeptide Inhibitors of Cathepsin G:  Optimization of a Novel β-Ketophosphonic Acid Lead by Structure-Based Drug Design

Michael N. Greco, Michael Hawkins, Eugene T. Powell et al. · Journal of the American Chemical Society · 2002 · 50 citations

Pharmacy, Medicinal Chemistry, Pharmacology +17