Leonora Niv‐Spector

Development and Characterization of High Affinity Leptins and Leptin Antagonists

Michal Shpilman, Leonora Niv‐Spector, Meirav Katz et al. · Journal of Biological Chemistry · 2010 · 139 citations · Full text

Life Sciences, Endocrinology, Pharmacology +13

Pegylated Leptin Antagonist Is a Potent Orexigenic Agent: Preparation and Mechanism of Activity

Eran Elinav, Leonora Niv‐Spector, Meirav Katz et al. · Endocrinology · 2009 · 104 citations · Full text

Medicine, Endocrinology, Pharmacology +16

Identification of the hydrophobic strand in the A–B loop of leptin as major binding site III: implications for large-scale preparation of potent recombinant human and ovine leptin antagonists

Leonora Niv‐Spector, Dana Gonen-Berger, Isabelle Gourdou et al. · Biochemical Journal · 2005 · 97 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +17

Mapping leptin-interacting sites in recombinant leptin-binding domain (LBD) subcloned from chicken leptin receptor

Leonora Niv‐Spector, N Raver, Miriam Friedman‐Einat et al. · Biochemical Journal · 2005 · 62 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +17

Large-scale preparation of biologically active mouse and rat leptins and their L39A/D40A/F41A muteins which act as potent antagonists

Gili Salomon, Leonora Niv‐Spector, Eugene Gussakovsky et al. · Protein Expression and Purification · 2005 · 50 citations

Medicine, Medicinal Chemistry, Pharmacology +10