Ayahisa Watanabe

Ribonuclease H1-dependent hepatotoxicity caused by locked nucleic acid-modified gapmer antisense oligonucleotides

Takeshi Kasuya, Shinichiro Hori, Ayahisa Watanabe et al. · Scientific Reports · 2016 · 106 citations · Full text

Targeted prevention of renal accumulation and toxicity of gentamicin by aminoglycoside binding receptor antagonists

Ayahisa Watanabe, Junya Nagai, Yoshinori Adachi et al. · Journal of Controlled Release · 2004 · 72 citations

Pharmaceutical Science, Urology, Renal Accumulation +9

Quantitative Imaging of A Therapeutic Peptide in Biological Tissue Sections by Maldi MS

Nozomi Takai, Yukari Tanaka, Ayahisa Watanabe et al. · Bioanalysis · 2013 · 34 citations

Comparative Characterization of Hepatic Distribution and mRNA Reduction of Antisense Oligonucleotides Conjugated with Triantennary N-Acetyl Galactosamine and Lipophilic Ligands Targeting Apolipoprotein B

Ayahisa Watanabe, Mado Nakajima, Naohisa Kitade et al. · Journal of Pharmacology and Experimental Therapeutics · 2016 · 27 citations

Pharmacokinetic–pharmacodynamic modeling for reduction of hepatic apolipoprotein B mRNA and plasma total cholesterol after administration of antisense oligonucleotide in mice

Ryosuke Shimizu, Mikiko Kitade, Takashi Kobayashi et al. · Journal of Pharmacokinetics and Pharmacodynamics · 2014 · 24 citations

Oxysterol, Pharmacokinetic Modeling, Biochemistry +9