Lilly Chai

Discovery of Aminoquinazolines as Potent, Orally Bioavailable Inhibitors of Lck:  Synthesis, SAR, and in Vivo Anti-Inflammatory Activity

Erin F. DiMauro, John Newcomb, Joseph J. Nunes et al. · Journal of Medicinal Chemistry · 2006 · 67 citations · Full text

Medicine, Medicinal Chemistry, Pharmacology +17

Structure-Based Design of Novel 2-Amino-6-phenyl-pyrimido[5′,4′:5,6]pyrimido[1,2-<i>a</i>]benzimidazol-5(6<i>H</i>)-ones as Potent and Orally Active Inhibitors of Lymphocyte Specific Kinase (Lck): Synthesis, SAR, and In Vivo Anti-Inflammatory Activity

Matthew W. Martin, John Newcomb, Joseph J. Nunes et al. · Journal of Medicinal Chemistry · 2008 · 64 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +17

Knockdown of human deubiquitinase PSMD14 induces cell cycle arrest and senescence

Annette T. Byrne, Rajashree McLaren, Paul Mason et al. · Experimental Cell Research · 2009 · 64 citations

Life Sciences, Cell Biology, Molecular Biology +14

Novel 2-Aminopyrimidine Carbamates as Potent and Orally Active Inhibitors of Lck:  Synthesis, SAR, and in Vivo Antiinflammatory Activity

Matthew W. Martin, John Newcomb, Joseph J. Nunes et al. · Journal of Medicinal Chemistry · 2006 · 61 citations · Full text

Medicine, Medicinal Chemistry, Pharmacology +16

Structure-Guided Design of Aminopyrimidine Amides as Potent, Selective Inhibitors of Lymphocyte Specific Kinase: Synthesis, Structure–Activity Relationships, and Inhibition of in Vivo T Cell Activation

Erin F. DiMauro, John Newcomb, Joseph J. Nunes et al. · Journal of Medicinal Chemistry · 2008 · 22 citations · Full text

Medicine, Medicinal Chemistry, Pharmacology +17