Mary Straub

Structure-based chemical modification strategy for enzyme replacement treatment of phenylketonuria

Wang Lin, Alejandra Gámez, Christineh N. Sarkissian et al. · Molecular Genetics and Metabolism · 2005 · 65 citations

Life Sciences, Biochemistry, Medicinal Chemistry +12

Structural Studies on Phenylalanine Hydroxylase and Implications Toward Understanding and Treating Phenylketonuria

Heidi Erlandsen, Marianne G. Patch, Alejandra Gámez et al. · PEDIATRICS · 2003 · 60 citations

Life Sciences, Biochemistry, Genetics +14

Development of Pegylated Forms of Recombinant Rhodosporidium toruloides Phenylalanine Ammonia-Lyase for the Treatment of Classical Phenylketonuria

Alejandra Gámez, Christineh N. Sarkissian, Lin Wang et al. · Molecular Therapy · 2005 · 49 citations · Full text

Life Sciences, Biochemistry, Pharmacology +15

Toward PKU Enzyme Replacement Therapy: PEGylation with Activity Retention for Three Forms of Recombinant Phenylalanine Hydroxylase

Alejandra Gámez, Lin Wang, Mary Straub et al. · Molecular Therapy · 2003 · 48 citations · Full text

Life Sciences, Biochemistry, Biotechnology +17