Ronald M. Laethem - Concepedia

Author

Ronald M. Laethem

Oregon Health & Science University

Also Known As

R Laethem, R M Laethem, R. Laethem, R.M. Laethem, Ronald Laethem, Ronald M. Laethem

Publications

990

Citations

H-Index

Concepts

All Affiliations

Oregon Health & Science University Research Triangle Park Foundation New York Medical College GlaxoSmithKline (Netherlands)Case Western Reserve University

About

Ronald M. Laethem is an author at Oregon Health & Science University specializing in biochemistry, medicine, and pharmacology.

Top Concepts

#	Concept	H-Index	Publications	Citations
1	Biochemistry	6	6	373
2	Medicine	5	5	363
3	Natural Sciences	3	3	276
4	Metabolism	2	2	252
5	Biomolecular Engineering	1	1	41

Ronald M. Laethem

Publications

975

Citations

H-Index

Page 1

	Year	Citations
Validation of Bupropion Hydroxylation as a Selective Marker of Human Cytochrome P450 2B6 Catalytic Activity Stephanie Faucette, Roy L. Hawke, Edward L. LeCluyse, Drug Metabolism and Disposition	2000	355
Formation of 19(S)-, 19(R)-, and 18(R)-hydroxyeicosatetraenoic acids by alcohol-inducible cytochrome P450 2E1 Ronald M. Laethem, Michael Balazy, John R. Falck, Journal of Biological Chemistry Medicinal ChemistryCytochrome P450 2E1BiochemistryArachidonic Acid MetabolismMedicine	1993	203
Toward Antibody-directed Enzyme Prodrug Therapy with the T268G Mutant of Human Carboxypeptidase A1 and Novel in VivoStable Prodrugs of Methotrexate Gary K. Smith, Sheila D. Banks, Todd A. Blumenkopf, Journal of Biological Chemistry	1997	65
Purification and properties of a cytochrome P450 arachidonic acid epoxygenase from rabbit renal cortex. Ronald M. Laethem, Carmen Laethem, Dennis R. Koop Journal of Biological Chemistry Molecular PharmacologyAldo-keto ReductaseAldehyde DehydrogenaseBiochemistryMedicine	1992	49
Identification of rabbit cytochromes P450 2C1 and 2C2 as arachidonic acid epoxygenases. Ronald M. Laethem, Dennis R. Koop Molecular Pharmacology	1992	46
Antibody-Directed Enzyme Prodrug Therapy with the T268G Mutant of Human Carboxypeptidase A1: In Vitro and in Vivo Studies with Prodrugs of Methotrexate and the Thymidylate Synthase Inhibitors GW1031 and GW1843 Larry A. Wolfe, Robert J. Mullin, Ronald M. Laethem, Bioconjugate Chemistry Adept SelectivityImmunotherapyTumor BiologyImmunochemistryAntibody Engineering	1999	41
Epoxidation of arachidonic acid as an active-site probe of cytochrome P-450 2B isoforms Ronald M. Laethem, James R. Halpert, Dennis R. Koop Biochimica et Biophysica Acta (BBA) - Protein Structure and Molecular Enzymology Cytochrome P-450 2BBiochemistryMedicineArachidonic AcidLipid Peroxidation	1994	38
Epoxidation of C18 unsaturated fatty acids by cytochromes P4502C2 and P4502CAA. Ronald M. Laethem, Michael Balazy, Dennis R. Koop Drug Metabolism and Disposition	1996	36
Expression and Characterization of Human Pancreatic Preprocarboxypeptidase A1 and Preprocarboxypeptidase A2 Ronald M. Laethem, Todd A. Blumenkopf, Michael Cory, Archives of Biochemistry and Biophysics Molecular PhysiologyPancreatic CancerBiochemistryMedicineGenetics	1996	32
Increases in Neutral, Mg2+-Dependent and Acidic, Mg2+-Independent Sphingomyelinase Activities Precede Commitment to Apoptosis and Are Not a Consequence of Caspase 3–Like Activity in Molt-4 Cells in Response to Thymidylate Synthase Inhibition by GW1843 Ronald M. Laethem, Yusuf A. Hannun, Supriya Jayadev, Blood	1998	31

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